S
- Sabinsville
- Sabula
- Sackett
- Saco
- Saco
- Sacramento
- Sadlers Corner
- Sadsburyville
- Saegers
- Saegertown
- Safe Harbor
- Sagamore
- Saginaw
- Sagon
- Saint Andrews Camp
- Saint Augustine
- Saint Benedict
- Saint Boniface
- Saint Clair
- Saint Clairsville
- Saint George
- Saint Johns
- Saint Joseph
- Saint Lawrence
- Saint Marys
- Saint Michael
- Saint Paul
- Saint Peters
- Saint Petersburg
- Saint Thomas
- Salco
- Salem
- Salem
- Salem
- Salemville
- Salford
- Salina
- Salisbury
- Salix
- Salladasburg
- Salona
- Saltillo
- Saltsburg
- Salunga
- Saluvia
- Sampson
- Sanatoga
- Sand Beach
- Sand Hill
- Sand Patch
- Sandrock
- Sandy
- Sandy Creek
- Sandy Hollow
- Sandy Hook
- Sandy Lake
- Sandy Plains
- Sandy Point
- Sandy Ridge
- Sandy Run
- Sandy Run
- Sandy Valley
- Sanford
- Sankertown
- Santiago
- Santoga
- Sarah Furnace
- Sardis
- Sartwell
- Sarver
- Sarverville
- Sassamansville
- Satterfield
- Saucon Valley Terrace
- Saulsburg
- Savage
- Saville
- Sawtown
- Sawyer City
- Saxonburg
- Saxton
- Saybrook
- Saylorsburg
- Saylorsville
- Sayre
- Scalp Level
- Scandia
- Scarlets Mill
- Scenery Hill
- Schaefferstown
- Schellsburg
- Schenley
- Schlusser
- Schnecksville
- Schoeneck
- Schofield Corners
- Schracktown
- Schubert
- Schultzville
- Schultzville
- Schuster Heights
- Schuyler
- Schuylkill Haven
- Schweibinzville
- Schwenksville
- Sciota
- Sciotavale
- Sconnelltown
- Scotch Hill
- Scotch Hollow
- Scotland
- Scot Run
- Scott
- Scott Center
- Scottdale
- Scott Haven
- Scottsville
- Scott Township
- Scranton
- Scranton Corners
- Scullton
- Seanor Benson
- Sebring
- Sechrist Mill
- Seeger Place
- Seelyville
- Seemsville
- Seger
- Seiple
- Seipstown
- Seisholtzville
- Seitzland
- Seldom Seen Corners
- Selinsgrove
- Selkirk
- Sellersville
- Sells Station
- Seltzer
- Seminole
- Seneca
- Sereno
- Sergeant
- Seven Fields
- Seven Pines
- Seven Points
- Seven Springs
- Seven Stars
- Seven Stars
- Seven Stars
- Seven Valleys
- Seward
- Sewickley
- Sewickley Heights
- Sewickley Hills
- Seyoc
- Shade Gap
- Shadeland
- Shades Glen
- Shadle
- Shado-Wood Village
- Shadow Shuttle
- Shady Grove
- Shady Plain
- Shaffer
- Shaffersville
- Shaft
- Shakespeare Club
- Shaler Township
- Shamburg
- Shamokin
- Shamokin Dam
- Shamrock
- Shamrock
- Shanesville
- Shanks Mill
- Shanksville
- Shannondale
- Shanor Heights
- Sharon
- Sharon Center
- Sharon Hill
- Sharpe
- Sharpsburg
- Sharpsville
- Shartlesville
- Shawanese
- Shaw Mines
- Shawmut
- Shawnee On Delaware
- Shawood Park
- Shaws Corners
- Shawville
- Shay
- Shaytown
- Sheakleyville
- Shearersburg
- Sheeder
- Sheffield
- Shehawken
- Shellsville
- Shelly
- Shellytown
- Shelmadine Springs
- Shelocta
- Shelvey
- Shenandoah
- Shenandoah Heights
- Shenango
- Shenks Ferry
- Shepherdstown
- Sheppton
- Sherman
- Shermans Dale
- Shermansville
- Sherrett
- Sheshequin
- Shettleston
- Shickshinny
- Shieldsburg
- Shillington
- Shiloh
- Shiloh
- Shimerville
- Shimerville
- Shimpstown
- Shinerville
- Shinglebury
- Shinglehouse
- Shingletown
- Shintown
- Shipmans Eddy
- Shippensburg
- Shippenville
- Shippingport
- Shiremanstown
- Shirks Corner
- Shirleysburg
- Shoaf
- Shoemakers
- Shoemakersville
- Shoemak Village
- Shohola
- Short Run
- Shortsville
- Shreiners
- Shrewsbury
- Shrivers Corners
- Shumans
- Shunk
- Sibleyville
- Sickles Corner
- Siddonsburg
- Sideling Hill
- Sidley
- Sidman
- Sigel
- Siglerville
- Sigmund
- Sigsbee
- Siko
- Silkworth
- Silvara
- Silver Creek
- Silverdale
- Silver Ford Heights
- Silver Mills
- Silver Spring
- Silverville
- Simmonstown
- Simpson
- Simpson Store
- Singersville
- Sinking Spring
- Sinnemahoning
- Sipes Mill
- Sipesville
- Sisterville
- Sitka
- Six Points
- Sizerville
- Skeltontown
- Skinners Eddy
- Skippack
- Skyline View
- Skytop
- Sky View Lake
- Slab
- Slabtown
- Slackwater
- Slatedale
- Slate Lick
- Slate Run
- Slate Valley
- Slatington
- Slickville
- Sligo
- Slippery Rock
- Sloan Gap
- Slocum
- Slocum Corners
- Slovan
- Smathers
- Smethport
- Smicksburg
- Smiley
- Smiley
- Smith
- Smith Bridge
- Smith Corner
- Smithdale
- Smithfield
- Smithland
- Smithmill
- Smith Mills
- Smithport
- Smiths Corner
- Smiths Station
- Smithton
- Smithtown
- Smithville
- Smock
- Smoke Run
- Smullton
- Snedekerville
- Snively Corners
- Snook
- Snow Hill Falls
- Snow Shoe
- Snows Mill
- S.N.P.J.
- Snyders
- Snydersville
- Snydertown
- Social Island
- Soldier
- Solebury
- Solomons Gap
- Somerfield
- Somerset
- Somers Lane
- Sonestown
- Songbird
- Sonman
- Sopertown
- Soradoville
- Soudersburg
- Souderton
- Southampton
- South Auburn
- South Bend
- South Bethlehem
- South Bradford
- South Branch
- South Canaan
- South Coatesville
- South Connellsville
- Southdale
- South Eaton
- South Fork
- South Gibson
- South Greensburg
- South Heights
- South Hill
- Southmont
- South Montrose
- South Mountain
- South New Castle
- South Park Township
- South Philipsburg
- South Pottstown
- South Renovo
- South Sterling
- South Strabane
- South Tamaqua
- South Towanda
- South Union
- Southview
- South Waverly
- Southwest
- Southwest Greensburg
- South Williamsport
- Spaces Corners
- Spangler
- Spangler (historical)
- Sparta
- Spartansburg
- Spechty Kopf
- Speeceville
- Speedwell
- Speers
- Spencer Corner
- Spencers Corners
- Spencertown
- Spindletown
- Spindley City
- Spinghope
- Splash Dam
- Sporting Hill
- Sporting Hill
- Spraggs
- Sprankle Mills
- Spring Bank
- Springboro
- Springbrook Corners
- Spring Church
- Spring City
- Spring Creek
- Springdale
- Springer Corners
- Springfield
- Springford Village
- Spring Garden
- Spring Glen
- Spring Grove
- Springhill
- Spring Hill
- Spring House
- Spring Meadow
- Spring Mills
- Spring Mount
- Spring Ridge
- Spring Run
- Springs
- Springtown
- Springtown
- Springtown
- Springvale
- Spring Valley
- Springville
- Sproul
- Spruce
- Spruce
- Spruce Creek
- Sprucetown
- Spry
- Squab Hollow
- Square Corner
- Stahlstown
- Stalker
- Standard Shaft
- Standing Stone
- Stanfordville
- Stanhope
- Stanley
- Stanton
- Stanton Corner
- Stanwood
- Starbrick
- Starford
- Star Junction
- Starkville
- Starlight
- Starners
- Starr
- Starr
- Star Rock
- Starrucca
- Starview
- Starville
- State College
- Statehill
- State Hill
- State Line
- State Line
- Steamburg
- Steam Valley
- Steelstown
- Steelton
- Steelville
- Steinsburg
- Stemlersville
- Sterling
- Sterling Run
- Sterrettania
- Steuben
- Steuben
- Stevens
- Stevens
- Stevens Point
- Stevenstown
- Stevensville
- Stewarton
- Stewartstown
- Stewartville
- Stickney
- Sticks
- Stiefler Corner
- Stifflertown
- Still Creek
- Stillwater
- Stilz
- Stines Corner
- Stobo
- Stockdale
- Stockertown
- Stoddartsville
- Stokesdale
- Stoneboro
- Stone Church
- Stone Glen
- Stoneham
- Stone House
- Stone House
- Stone House Corner
- Stonemont
- Stoner
- Stonerstown
- Stonersville
- Stoney Run
- Stonington
- Stonybreak
- Stony Creek
- Stony Fork
- Stony Point
- Stony Point
- Stony Point
- Stony Run
- Stoops Ferry
- Stormstown
- Stormville
- Stouchsburg
- Stoufferstown
- Stouts
- Stover
- Stovers Mill
- Stoverstown
- Stowe
- Stowell
- Stowe Township
- Stoystown
- Strabane
- Strables Corners
- Strafford
- Straight Creek
- Strangford
- Strasburg
- Strattanville
- Straub
- Strausstown
- Strawberry Ridge
- Strawbridge
- Strawn
- Stremmels
- Strickersville
- Strickhousers
- Strickler
- Strinestown
- Stringtown
- Strobleton
- Strodes Mills
- Stronach
- Strongstown
- Stroudsburg
- Strouptown
- Stull
- Stump Creek
- Sturgeon
- Suedberg
- Sugar Camp
- Sugarcreek
- Sugar Grove
- Sugar Hill
- Sugar Notch
- Sugar Run
- Sugartown
- Sulphur Springs
- Sulvan Dell
- Sumerson
- Summerhill
- Summer Hill
- Summerville
- Summit
- Summit
- Summit
- Summit
- Summit Hill
- Summit Lawn
- Summit Mills
- Summit Station
- Sunbury
- Suncliff
- Sundale
- Sunderlinville
- Sundy Place
- Sunflower
- Sunnyburn
- Sunol
- Sunset Pines
- Sunset Valley
- Sunshine
- Sunshine
- Sun Valley
- Sunville
- Superior
- Superior
- Suplee
- Surveyor
- Suscon
- Susquehanna
- Susquehanna Trails
- Sutersville
- Swarthmore
- Swarts
- Swartzville
- Sweden Valley
- Swedetown
- Sweet Valley
- Swengal
- Swiftwater
- Swissdale
- Swissmont
- Swissvale
- Swoyersville
- Syberton
- Sybertsville
- Sycamore
- Sycamore Mills
- Sykesville
- Sylmar
- Sylvan
- Sylvan Grove
- Sylvania
- Sylvan Lane
- Sylvester
- Sylvis
- Syndersburg